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: The Capicua repressor a general sensor of ...

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This work is supported by ICREA, Ministerio de Ciencia e Innovación [grant number BFU200801875 to ] and Generalitat de Catalunya [grant number 2009SGR1075 to ]; the National Institutes of Health and National Science Foundation to ; the National Institutes of Health (National Institute of General Medical Sciences) [grant number R01GM086537 to and ]; the Israel ...

Capicua DNAbinding sites are general response elements ...

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· Capicua DNAbinding sites are general response elements for RTK signaling in Drosophila. ... 2007) and the Groucho (Gro) corepressor (Hasson et al., 2005; Cinnamon et al., 2008; Cinnamon and Paroush, ... The Capicua repressora general sensor of …

The Capicua repressor a general sensor of RTK signaling ...

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This work is supported by ICREA, Ministerio de Ciencia e Innovación [grant number BFU200801875 to ] and Generalitat de Catalunya [grant number 2009SGR1075 to ]; the National Institutes of Health and National Science Foundation to ; the National Institutes of Health (National Institute of General Medical Sciences) [grant number R01GM086537 to and …

The Capicua repressor a general sensor of RTK signaling ...

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The Capicua repressor a general sensor of RTK signaling in development and disease: Autor: Jiménez, Gerardo; Shvartsman, Stanislav Y.; Paroush, Ze''ev: Palabras clave: Cell proliferation CIC MAPK RTK signaling Capicua: Fecha de publicación: 2012: Editor: Company of Biologists: Citación: Journal of Cell Science 125(6): 13831391 (2012) Resumen:

The Capicua repressora general sensor of RTK signaling ...

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Receptor tyrosine kinase (RTK) signaling pathways control multiple cellular decisions in metazoans, often by regulating the expression of downstream genes. In Drosophila melanogaster and other systems, Etwentysix (ETS) transcription factors are considered to be the predominant nuclear effectors of RTK pathways. Here, we highlight recent progress in identifying the HMG …

Regulation and function of capicua in mammals ...

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· Ajuria, L. et al. Capicua DNAbinding sites are general response elements for RTK signaling in Drosophila. Development 138 , 915–924 (2011). …

The Capicua repressor – a general sensor of RTK signaling ...

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Fig. 1. Structural features of Drosophila and human CIC proteins. Two main isoforms, short (CICS) and long (CICL), are present in each species (Lam et al., 2006). In Drosophila, CICS fulfils most known CIC functions, whereas CICL appears to have specific roles in oogenesis (Rittenhouse and Berg, 1995; Jimenez et al., 2000; Goff et al., 2001; Roch et al., 2002; …

The Capicua repressora general sensor of RTK signaling ...

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· Here, we highlight recent progress in identifying the HMGbox protein Capicua (CIC) as a key sensor of RTK signaling in both Drosophila and mammals. Several studies have shown that CIC functions as a repressor of RTKresponsive genes, keeping them silent in …

The Capicua repressor A general sensor of RTK signaling ...

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Here, we highlight recent progress in identifying the HMGbox protein Capicua (CIC) as a key sensor of RTK signaling in both Drosophila and mammals. Several studies have shown that CIC functions as a repressor of RTKresponsive genes, keeping them …

The Capicua repressor a general sensor of RTK signaling ...

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Supporting: 4, Mentioning: 133 SummaryReceptor tyrosine kinase (RTK) signaling pathways control multiple cellular decisions in metazoans, often by regulating the expression of downstream genes. In Drosophila melanogaster and other systems, Etwentysix (ETS) transcription factors are considered to be the predominant nuclear effectors of RTK pathways.

The Capicua repressor A general sensor of RTK signaling ...

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INFORME DEL DIRECTOR Función del Represor Capicua en la ...

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Participación de Leiore Ajuria Astobiza en los artículos presentados en su Tesis Doctoral . et al. (2011) Capicua DNA binding sites are general response elements for RTK signaling in , 915924.. Este artículo presenta un extenso trabajo experimental que ha sido realizado en su mayor parte por Leiore Ajuria.

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